Press the Attack
Hitting an enemy champion 3 consecutive times deals bonus damage and amplifies your damage until you leave combat with champions.
Runes
Every keystone and minor rune across the five trees.
Precision
Keystones 
Lethal Tempo
Attacking an enemy champion grants you Attack Speed, up to 6 stacks. At max stacks, deal bonus adaptive damage On-Attack.
Fleet Footwork
Attacking and moving builds Energy stacks. At 100 stacks, your next attack heals you and grants increased MS.
Conqueror
Gain stacks of adaptive force when attacking enemy champions. After reaching 12 stacks, heal for a portion of damage you deal to champions.
Row 1 
Absorb Life
Killing a target heals you.
Triumph
Takedowns restore 5% of your missing health and grant an additional 20 gold.
Presence of Mind
Restore a small amount of mana or energy when damaging an enemy champion. Takedowns restore mana or energy.
Row 2 
Legend: Alacrity
Takedowns on enemies grant permanent Attack Speed.
Legend: Haste
Takedowns on enemies grant permanent Basic Ability Haste.
Legend: Bloodline
Takedowns on enemies grant permanent Life Steal, up to a cap. Once the cap is reached, increase your max health. Weaker earlier but stronger later game than other Legend Runes.
Row 3 
Coup de Grace
Deal more damage to low health enemy champions.
Cut Down
Deal more damage to high health enemy champions.
Last Stand
Deal more damage to champions while you are low on health.
Domination
Keystones 
Electrocute
Hitting a champion with 3 separate attacks or abilities in 3s deals bonus adaptive damage.
Dark Harvest
Damaging a low health champion inflicts adaptive damage and harvests a soul from the victim.
Hail of Blades
Gain a large amount of Attack Speed and bonus true damage for the first 3 attacks made against enemy champions.
Row 1 
Cheap Shot
Deal bonus true damage to enemy champions with impaired movement or actions.
Taste of Blood
Heal when you damage an enemy champion.
Sudden Impact
Damaging basic attacks and abilities deal bonus true damage to enemy champions after using a dash, leap, blink, teleport, or when leaving stealth.
Row 2 
Sixth Sense
On a long Cooldown, automatically sense a nearby untracked and unseen ward, tracking it for the team.
Level 11: Also reveal the ward for 10s.
Grisly Mementos
Collect 1 memento on champion takedowns, up to 18 total.
Gain 6 Trinket Haste for each collected.
Deep Ward
Your wards in the enemy jungle are Deep, gaining Health and Duration.
Level 9: Wards in the river are also Deep.
Row 3 
Treasure Hunter
Unique takedowns grant additional gold the first time they are collected.
Relentless Hunter
Unique takedowns grant permanent out of combat MS.
Ultimate Hunter
Unique takedowns grant permanent cooldown reduction on your Ultimate.
Sorcery
Keystones 
Summon Aery
Your attacks and abilities send Aery to a target, damaging enemies or shielding allies.
Arcane Comet
Damaging a champion with an ability hurls a damaging comet at their location.
Stormraider's Surge
Dealing 25% of a champion's maximum health grants a burst of MS and Slow Resist.
Deathfire Touch
Damaging a champion with an ability burns them over time.
Row 1 
Axiom Arcanist
Your Ultimate has increased damage, healing, and shielding. Scoring a takedown on an enemy champion reduces your Ultimate's current cooldown.
Manaflow Band
Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Nimbus Cloak
After casting a Summoner Spell, gain a short Move Speed increase that allows you to pass through units.
Row 2 
Transcendence
Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.
Celerity
All Move Speed bonuses are 7% more effective on you and gain 1% Move Speed.
Absolute Focus
While above 70% health, gain extra adaptive damage.
Row 3 
Scorch
Your first damaging ability hit every 10s burns champions.
Waterwalking
Gain MS and AP or AD, adaptive in the river.
Gathering Storm
Gain increasing amounts of AD or AP, adaptive over the course of the game.
Resolve
Keystones 
Grasp of the Undying
Every 4s your next attack on a champion deals bonus magic damage, heals you, and permanently increases your health.
Aftershock
After immobilizing an enemy champion gain defenses and later deal a burst of magic damage around you.
Guardian
Guard allies you cast spells on and those that are very nearby. If you or a guarded ally would take damage based on level, you're both granted a shield.
Row 1 
Demolish
Your third attack against turrets deals bonus damage.
Font of Life
Impairing the movement of an enemy champion heals nearby allied champions.
Shield Bash
Whenever you gain a shield, your next basic attack against a champion deals bonus adaptive damage.
Row 2 
Conditioning
After 12 min gain +8 Armor and +8 Magic Resist and increase your Armor and Magic Resist by 3%.
Second Wind
After taking damage from an enemy champion heal back some missing health over time.
Bone Plating
After taking damage from an enemy champion, the next 3 spells or attacks you receive from them deal 30-60 (based on level) less damage.
Duration: 1.5s
Cooldown: 55s
Row 3 
Overgrowth
Gain permanent max health when minions or monsters die near you.
Revitalize
Gain 5% Heal and Shield Power.
Heals and shields you cast or receive are 10% stronger on targets below 40% health.
Unflinching
Gain Armor and Magic Resist when receiving crowd control.
Inspiration
Keystones 
Glacial Augment
Immobilizing an enemy champion will cause 3 glacial rays that slow nearby enemies and reduce their damage to your allies.
Unsealed Spellbook
Swap Summoner Spells while out of combat. Swapping to unique Summoner Spells will increase the rate at which you can make future swaps.
First Strike
When you initiate champion combat, deal 7% extra damage for 3 seconds and gain gold based on damage dealt.
Row 1 
Hextech Flashtraption
While Flash is on cooldown it is replaced by Hexflash.
Hexflash: Channel, then blink to a new location.
Magical Footwear
You get free boots at 12 min but you cannot buy boots before then. Each takedown you get makes your boots come 45s sooner.
Cash Back
Get some gold back when you purchase Legendary Items.
Row 2 
Triple Tonic
Upon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.
Time Warp Tonic
Potions grant some restoration immediately.
Biscuit Delivery
Gain a free Biscuit every 2 min, until 6 min. Consuming or selling a Biscuit permanently increases your max health and restores health.
Row 3 
Cosmic Insight
+18 Summoner Spell Haste
+10 Item Haste
Approach Velocity
Bonus MS towards nearby enemy champions that are movement impaired, increased for enemy champions that you impair.
Jack Of All Trades
For each different stat gained from items, gain one Jack stack. Each stack grants you 1 Ability Haste.
Gain bonus Adaptive Force at 5 and 10 stacks.